tag:blogger.com,1999:blog-1784979337240753632024-03-13T00:01:27.979-07:00DENGUEanahttp://www.blogger.com/profile/17624273856608238157noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-178497933724075363.post-82452850148196348292010-02-20T12:33:00.000-08:002010-02-20T12:35:18.980-08:00CAUSE<p align="justify"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhAXfnpZ3gzZHbwt4d_c_4wYfQMUUwdwC7FzeYaG4ewH4WuU5TS8g9akm1jucMslQQUwHtXn131fmRbnJ0GlfMlnwGgrnHn3hu1vFcPRP7lHnG6xBmywe2Q51_Zoc9C1yxTyStX5GDu84oy/s1600-h/dengue_asia[1].gif"><img id="BLOGGER_PHOTO_ID_5440426928430184194" style="FLOAT: left; MARGIN: 0px 10px 10px 0px; WIDTH: 200px; CURSOR: hand; HEIGHT: 130px" alt="" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhAXfnpZ3gzZHbwt4d_c_4wYfQMUUwdwC7FzeYaG4ewH4WuU5TS8g9akm1jucMslQQUwHtXn131fmRbnJ0GlfMlnwGgrnHn3hu1vFcPRP7lHnG6xBmywe2Q51_Zoc9C1yxTyStX5GDu84oy/s200/dengue_asia%5B1%5D.gif" border="0" /></a></p><br /><br /><div align="justify"><span style="color:#ff99ff;">Dengue fever is caused by Dengue virus (DENV), a mosquito-borne flavivirus. DENV is an ssRNA positive-strand virus of the family Flaviviridae; genus Flavivirus. There are four serotypes of DENV. The virus has a genome of about 11000 bases that codes for three structural proteins, C, prM, E; seven nonstructural proteins, NS1, NS2a, NS2b, NS3, NS4a, NS4b, NS5; and short non-coding regions on both the 5' and 3' ends.</span></div>anahttp://www.blogger.com/profile/17624273856608238157noreply@blogger.com0tag:blogger.com,1999:blog-178497933724075363.post-71629083909016594982010-02-20T12:10:00.000-08:002010-02-20T12:20:57.214-08:00SIGNS AND SYMPTONS<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj85WcqqohJD4Uj0zJ9-5mHLduc2a7y6u3Stze9pjVeA9FI3_j1FtLM45qMWgPcJod92sM4Erda6WuULEhcnIHqPFKWpyZFoBmMICa82DBIOWPRwba2Kkaya2zBatIxv8A_oqsKgGBTKey1/s1600-h/dengue[1].jpg"><img id="BLOGGER_PHOTO_ID_5440423162553438498" style="FLOAT: left; MARGIN: 0px 10px 10px 0px; WIDTH: 128px; CURSOR: hand; HEIGHT: 191px" alt="" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj85WcqqohJD4Uj0zJ9-5mHLduc2a7y6u3Stze9pjVeA9FI3_j1FtLM45qMWgPcJod92sM4Erda6WuULEhcnIHqPFKWpyZFoBmMICa82DBIOWPRwba2Kkaya2zBatIxv8A_oqsKgGBTKey1/s320/dengue%5B1%5D.jpg" border="0" /></a><br /><div align="justify"><span style="color:#000000;">The disease manifests as a sudden onset of severe headache, muscle and joint pains (</span><a title="Myalgia" href="http://en.wikipedia.org/wiki/Myalgia"><span style="color:#000000;">myalgias</span></a><span style="color:#000000;"> and </span><span style="color:#000000;">arthralgias</span><span style="color:#000000;">—severe pain that gives it the nickname break-bone fever or bonecrusher disease), </span><span style="color:#000000;">fever</span><span style="color:#000000;">, and </span><span style="color:#000000;">rash</span><span style="color:#000000;">.</span><span style="color:#000000;"> The dengue rash is characteristically bright red </span><span style="color:#000000;">petechiae</span><span style="color:#000000;"> and usually appears first on the lower limbs and the chest; in some patients, it spreads to cover most of the body. There may also be </span><span style="color:#000000;">gastritis</span><span style="color:#000000;"> with some combination of associated </span><span style="color:#000000;">abdominal pain</span><span style="color:#000000;">, </span><span style="color:#000000;">nausea</span><span style="color:#000000;">, </span><span style="color:#000000;">vomiting</span><span style="color:#000000;">, or </span><span style="color:#000000;">diarrhea</span><span style="color:#000000;">.<br />Some cases develop much milder symptoms which can be misdiagnosed as </span><span style="color:#000000;">influenza</span><span style="color:#000000;"> or other viral infection when no rash is present. Thus travelers from tropical areas may pass on dengue inadvertently, having not been properly diagnosed at the height of their illness. Patients with dengue can pass on the infection only through mosquitoes or blood products and only while they are still </span><span style="color:#000000;">febrile</span><span style="color:#000000;">. The classic dengue fever lasts about two to seven days, with a smaller peak of fever at the trailing end of the disease (the so-called "biphasic pattern"). Clinically, the </span><span style="color:#000000;">platelet</span><span style="color:#000000;"> count will drop until the patient's temperature is normal. Cases of DHF also show higher fever, variable hemorrhagic phenomena, </span><span style="color:#000000;">thrombocytopenia</span><span style="color:#000000;">, and </span><span style="color:#000000;">hemoconcentration</span><span style="color:#000000;">. A small proportion of cases lead to </span><span style="color:#000000;">dengue shock syndrome</span><span style="color:#000000;"> (DSS) which has a high mortality rate.</span></div>anahttp://www.blogger.com/profile/17624273856608238157noreply@blogger.com0tag:blogger.com,1999:blog-178497933724075363.post-36551492830526379992010-02-20T11:25:00.000-08:002010-02-20T12:10:04.812-08:00DENGUE<div align="justify"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgqskZCMn5g46v6nHP6KH8NXmhyBITfvbMCorlrTzcxOVJKz5UT_g0-uFQD-RJrghJNWm8ki3o1Q11RgmiupU3_55k_monqk7ohquA8RWA6RCVfdgZT0lIYY_EN8SoTFl58G3XMG7bhceAt/s1600-h/220px-Dengue[1].jpg"><img id="BLOGGER_PHOTO_ID_5440418458425398770" style="FLOAT: right; MARGIN: 0px 0px 10px 10px; WIDTH: 169px; CURSOR: hand; HEIGHT: 149px" alt="" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgqskZCMn5g46v6nHP6KH8NXmhyBITfvbMCorlrTzcxOVJKz5UT_g0-uFQD-RJrghJNWm8ki3o1Q11RgmiupU3_55k_monqk7ohquA8RWA6RCVfdgZT0lIYY_EN8SoTFl58G3XMG7bhceAt/s320/220px-Dengue%5B1%5D.jpg" border="0" /></a> <span style="color:#33cc00;">Dengue fever and dengue hemorrhagic fever (DHF) are acute febrile diseases which occur in the tropics can be life-threatening, and are caused by four closely related virus serotypes of the genus Flavivirus, family Flaviviridae. It is also known as breakbone fever. It occurs widely in the tropics, including northern Argentina, northern Australia, the entirety of Bangladesh, Barbados, Bolivia, Brazil, Cambodia, Costa Rica, Dominican Republic, Guatemala, Guyana, Honduras, India, Indonesia, Jamaica, Laos, Malaysia, Mexico, Micronesia, Pakistan, Panama, Paraguay, Philippines, Puerto Rico, Samoa, Singapore, Sri Lanka, Suriname, Taiwan, Thailand, Trinidad, Venezuela and Vietnam, and increasingly in southern China. Unlike malaria, dengue is just as prevalent in the urban districts of its range as in rural areas. Each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. Dengue is transmitted to humans by the Aedes aegypti or more rarely the Aedes albopictus mosquito, which feed during the day.<br />The WHO says some 2.5 billion people, two fifths of the world's population, are now at risk from dengue and estimates that there may be 50 million cases of dengue infection worldwide every year. The disease is now endemic in more than 100 countries.<br /></span></div><div align="justify"><br /><br /></div><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjlJ-M9LK3-t27SpUcKzWgUDbxNf3BvauWfOI9oATRU2nyqQM20XckLWwvG3IaxZigfsOBr5EYb1ZBG3Q-JOvq4lJubty0BlxGzGa9pLIq2RpeLyiTvChI_YaE0ZBmg-AVmLdwwPLLtwuX2/s1600-h/220px-Dengue[1].jpg"></a>anahttp://www.blogger.com/profile/17624273856608238157noreply@blogger.com0